A bluish macular discoloration was noted over both sides of the face. Files are available under licenses specified on their description page. Pdf we describe an extraordinary case of a nevus of ota with intraoral mucosal involvement. Nevus of ota is a blue dubious discuss hyperpigmentation that occurs on the face, most often appearing on the white of the eye. Sturgeweber and klippeltrenaunay syndrome with nevus of. Horis nevus is an acquired benign dermal melanocytosis. A 40 yearold male presented to the department of ophthalmology of a secondary care institute of the hilly state with a history of pigmentary changes. In this paper, the majority of nevi of ota were classified in class 1 and 2 of tanino. Mar 26, 2019 nevi of ota and ito occur most frequently in individuals of asian descent, with an estimated prevalence of 0. Sep 28, 2011 nevus of ito is a colored birth mark that is usually slatebrown or bluegray. Nevus of ota a rare pigmentation disorder with intraoral. We report a case of successful treatment of an ota nevus in a patient with fitzpatrick skin type iv with the novel 532nm solidstate picosecond laser after 2 treatments. Large tan macule dotted with numerous superimposed small dark nevi. Yag 43 deliver a clinically significant amount of energy and at the same time obtain a wide area of rejuvenation, a larger 6 mm spot size and low fluence were used during the last two treatments.
Pathologically, it is a dermal melanocytic hamartoma that presents with unilateral or bilateral, brown or blue discoloration on the facial skin in. Neurofibromatosis associated with nevus of ota and choroidal melanoma. Oculodermal melanocytosis nevus of ota contributor. Nevus of ota a 6yearold girl presented with an asymptomatic dark patch over the left side of her face. Becker nevus syndrome is a phenotype characterized by the fundamental presence of beckers. Otas nevus is usually congenital but may appear in. Unlike nevus of ota, the pigmentation occurs bilaterally and symmetrically, has a late onset in adulthood, and does not involve the mucosa. Clinically, nevus of ota is distributed along the ophthalmic and maxillary divisions of the trigeminal nerve and presents as a blue or gray patch on the face. These are unusual skin discolorations in which melanocytes are found deeper than normal. Becker nevus syndrome is a phenotype characterized by the fundamental presence of beckers nevus with ipsilateral hypoplasia of the breast or other skin, skeletal. Nevus of ota nevus fuscoceruleus ophthalmomaxillaris is a bluegray or brown irregular, often spotted skin discoloration located on the face in the distribution of the first and second branches of the trigeminal nerve i. Treatment of nevus of ota by qswitched ruby laser mayo.
Comparison of characteristics of acquired bilateral. Orbital malignant melanoma and oculodermal melanocytosis. Since then, this melanocytic nevus has been widely known as nevus of ota. Dec 11, 2017 treatment for giant congenital nevus depends on the age of the affected individual as well as the size, location, and thickness of the nevus. Nevi of ota and ito occur most frequently in individuals of asian descent, with an estimated prevalence of 0. Mar 22, 2020 nevus of ota is referred to as nevi of ota in plural form. Nevus or nevi if multiple is a nonspecific medical term for a visible, circumscribed, chronic lesion of the skin or mucosa. When small nevi are removed, the surrounding skin can often be pulled together with stitches. For successful treatment of nevus of ota, fluence settings between 2. Brownishblack diffuse pigmented areas were also noticed on the buccal mucosa of the same side. Request pdf laser treatment of nevus of ota nevus of ota is an often disfiguring dermal melanocytosis of the face most prevalent in the japanese population. Nevus of ota with contralateral cerebral melanoma jama network. Malignant melanoma of the choroid in the nevus of ota.
The first case of phakomatosis pigmentovascularis figure 6 was described in 1920 in a patient with generalized hemangioma and nevus. Nevus of ota is localized in the region of the first and second branches of the trigeminal nerve and is bilateral in 5% of cases. Nevus of ota is a a melanocytic proliferation that occurs around the eye which i occasionally encounter in both my the woodlands dermatology and conroe dermatology offices. The patient was a 25yearold japanese woman with an extensive nevus flammeus which extended primarily over the left side of her face and the right side of the trunk and extremities. This type of birthmark is usually located on the shoulder and upper arm area on one side of the body. Nevus of ota, also known as nevus fuscoceruleus opthalmomaxillaris, represents a benign partially confluent macular brownblue pigmentation of the skin and mucous membranes in the distribution of the first and second branches of the trigeminal nerve. Nevus of ota nevus fuscocoeruleus ophthalmomaxillaris or ocular dermic melanocytosis is a clinical condition characterized by bluedark pigmentation, greenblue, violet, or tan spots in the eyes andor on the faces skin and lids. The site of the nevus may reflect the locational preference of the greater component of the nevus the most common site is the torso around 35% of the cases including the abdomen, chest, and back other common sites include the head and neck region in 24% of the cases.
The term nevus is applied to a number of conditions caused by neoplasias and hyperplasias of melanocytes, as well as a number of pigmentation disorders, both hypermelanotic containing increased melanin, the pigment responsible for skin color and hypomelanotic containing decreased melanin. Clinicalgreyblue sometimes black colored patch or papula. Clinically, nevus of ota presents as a blue or gray patch on the face, which is congenital or acquired and is within the distribution of the ophthalmic and maxillary branches of the trigeminal nerve. Nevus of ota is a dermal melanocytosis originally described by ota and tanino in 1939. A nevus plural nevi is a mole on the skin that can occur on any part of the body. A melanose conjuntivoepiscleral foi reconhecida no olho direito em cinco. A nevus ne ves common skin growthcomposedofspecial pigmentproducing cells called nevomelanocytes. Extracutaneous involvement has been reported, especially ocular involvement. Review on acquired bilateral nevus of otalike macules. We performed a retrospective analysis of case files and photographic. Nevus of ito also is a dermal melanocytic aberration that exclusively affects the shoulders and often occurs in association with nevus of ota. Comparison of characteristics of acquired bilateral nevusof. Th cowan, m balistockythe nevus of ota or oculodermal melanocytosis. Nevus of ito is a colored birth mark that is usually slatebrown or bluegray.
It also occurs on the forehead, nose, cheek, periorbital region, and temple. Pdf nevus of ota clinicalophthalmological findings researchgate. Acquired bilateral nevus of ota like macules abnom is a dermal pigmented lesion common in individuals of oriental origin. Aug 20, 2014 nevus of ota is a dermal melanocytosis seen along the distribution of ophthalmic and maxillary divisions of the trigeminal nerve. The nevus of ota appears as increased pigmentation of one eye and its eyelids. Nevus of ota, which originally was described by ota and tanino in 1939, is a hamartoma of dermal melanocytes.
Treatment of nevus of ota with 1064 nm qswitched nd. Yag laser qsnyl has been used successfully to treat a variety of benign, dermal, pigmented lesions, including nevus of ota lesions. Epidermal nevi are typically seen at birth or develop in early childhood. A congenital melanocytic nevus is a birthmark, it can be defined as small, large, and giant. Ota, known by the pen name mokutaro kinoshita, was a japanese doctor who first described the condition in 1939, which is why it is named after him. The photo above shows significant clearance after serial. Nevus of ota, or nevus fuscoceruleus ophthalmomaxillaris, is a dermal melanocytic hamartoma that presents as bluish hyperpigmentation along the first or second branches of the trigeminal nerve. During childhood, adolescence, or adulthood, secondary macules or papules form within the patch. They are not genetic, and there are several different types. Nevus of ota often occurs in association with nevus of ito which is a dermal melanocytic condition affecting the shoulder area. The age of onset is bimodal, with larger peak at birth or soon after and a smaller peak at adolescence.
Only 12 cases so far have been reported in english literature and it is rare in indian subcontinent. Although extracutaneous complications and melanoma can occur, they are uncommon, and most patients with nevus of ota suffer from the psychological. Nevus of ota no is a relatively common pigmentary disorder in asians. Nevus of ota, a benign melanocytic pigmentary disorder with rare malignant transformation potential, affects 0. Nevus of ota oculodermal melanocytosis, nevus fuscoceruleus ophthalmomaxillaris is a dermal melanocytic hamartoma that presents as bluishslategray hyperpigmentation along the first or second branch of the trigeminal nerve. Patients with the nevus of ota should be examined at least every 6 months by an eyecancer specialist and a neurologist. Are qswitched lasers for nevus of ota really effective in.
Abstract the blue nevus is an abnormal collection of functioning dermal melanocytes and melanin. Among these, nevus of ota and abnom are clinically similar and both diseases cause aesthetic problems as they develop on the face and are not selflimited. There are several types of epidermal nevus that are defined in part by the type of epidermal cell. Taninos classification is an old but tacit consensus to delineate the. Clinically, horis nevus occurs as multiple brown to gray macules or gray to bluish patches on the face after puberty and is distributed at the malar areas, forehead, temple, eyelids, alae of the nose and root of the nose. Surgery may be done to remove the nevus, particularly when there is a concern that it may develop into a melanoma. Oculodermal melanocytosis, also known as nevus of ota, is a condition of excessive pigmentation of the uvea, sclera, episclera, and eyelids secondary to an increase in the number of normal melanocytes. Commonly it is localized on the head, back, hands and legs with size to 1 cm. The results in pigmented skin are not as good as in the western skin, in terms of number of sittings and percentage of improvement, as the inherent pigmentation in the epidermis interferes with the laser beam before it targets the nevus cells. The eyelid is darkened, pigment can be observed on the white of the eye and that iris may be darker compared to the contralateral iris.
In 1916, pusey described the case of a chinese student with both scleral and facial pigmentation. Reed nevus is a benign melanocytic neoplasm, which usually manifests as a solitary spot or like a dark brown or black tumor, its usual level topography are lower extremities. Nevus of ito genetic and rare diseases information center. The topic naevus of ota and ito you are seeking is a synonym, or alternative name, or is closely related to the medical condition nevus of ota. Also called oculodermal melanosis or nevus fuscoceruleus ophthalmomaxillaris similar to nevus of ito except for location ito in shoulder, side of neck and supraclavicular areas, within the distribution of the lateral supraclavicular nerve and lateral cutaneous brachial nerves. Beckers nevus syndrome, malignant melanoma, nevus of ota, nevus of ito, spitz nevus, blue nevus, and congenital smooth muscle hamartome see these terms. The skin innervated by the first and second branch of the trigeminal nerve is typically involved. On examination, mottled bluegray macules were seen over the left cheek extending to. The nevi develop from melanocytes, which are the cells in the bottom layer of the epidermis, or the skins outer layer. It is described only in the orientals and is much more common in females. Fifty patients of nevus of ota underwent multiple treatments average 6 sessions carried out over a period of 1year with a qswitched nd. Successful treatment of ota nevus with the 532nm solid.
Ocular findings in oculodermal melanocytosis jama network. Nevus of ota no, or oculodermal melanocytosis, affects about 0. The efficacy of the qswitched ruby laser 694 nm, 40 nsec as a therapy for nevus of ota was investigated. Nevus depigmentosus nevus depigmentosus is characterized by a congenital, asymptomatic, nonprogressive, hypopigmented macule or patch that is stable in shape, distribution, texture, and relative size throughout life. Nevus of ito is less common than nevus of ota, although the true incidence is unknown. The statement that the results in type 45 skin are better than type skin is not borne in respect to the published evidence. The presence of pigmentation on the skin over pinna and oral. It is an unusual birthmark in which the melanocytes pigment cells are found deeper than normal in the skin. It usually presents at birth or early childhood, first as a cafe au laitlike lightly pigmented flat patch. Very often, nevus of ota occurs unilaterally in blacks and oriental women 4. Nevus of ota is mostly unilateral and located around the oral mucosa and mucous of the eye. Moreover, traditional treatments are largely palliative or risk permanent pigmentary changes andor scarring. Nevus of ota is the commonest in asian patients and affects between 0.
Nevus of ota is referred to as nevi of ota in plural form. The lesion is usually stable with no tendency to increase with time. Nevus of ito genetic and rare diseases information. Media in category nevus of ota the following 6 files are in this category, out of 6 total. A 40 yearold male presented to the department of ophthalmology of a secondary care institute of the hilly state with a history of pigmentary changes in his left eye and left upper part of cheek since birth. More accurately grouped with dermal melanocytoses nevus of ito, nevus of ota, hori nevus, socalled mongolian spot emedicine nevi of ota and ito although melanocytic, it is not a true nevus different entity from hypomelanosis of ito, a neurocutaneous disorder j child neurol 2000. All structured data from the file and property namespaces is available under the creative commons cc0 license.
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